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Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models

BACKGROUND: The role of the microbiome has become synonymous with human health and disease. Bile acids, as essential components of the microbiome, have gained sustained credibility as potential modulators of cancer progression in several disease models. At physiological concentrations, bile acids ap...

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Detalles Bibliográficos
Autores principales: Phelan, J. P., Reen, F. J., Dunphy, N., O’Connor, R., O’Gara, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946243/
https://www.ncbi.nlm.nih.gov/pubmed/27416726
http://dx.doi.org/10.1186/s12885-016-2528-2