Novel molecular triggers underlie valproate-induced liver injury and its alleviation by the omega-3 fatty acid DHA: role of inflammation and apoptosis

BACKGROUND/AIM: Hepatic injury is a hallmark adverse reaction to Valproate (VPA), a common used drug in the management of numerous CNS disorders, including epilepsy. DHA has a myriad of health benefits, including renal- and hepato-protective effects. Unfortunately, however, the underpinnings of such...

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Detalles Bibliográficos
Autores principales: El-Mowafy, Abdalla M., Katary, Mohamed M., Pye, Chelsey, Ibrahim, Ahmed S., Elmarakby, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946287/
https://www.ncbi.nlm.nih.gov/pubmed/27441301
http://dx.doi.org/10.1016/j.heliyon.2016.e00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946287/
https://www.ncbi.nlm.nih.gov/pubmed/27441301
http://dx.doi.org/10.1016/j.heliyon.2016.e00130

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