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Size effect of engineered islets prepared using microfabricated wells on islet cell function and arrangement

Pancreatic islets are heterogeneous clusters mainly composed of α and β cells, and these clusters range in diameter from 50 to several hundred micrometers. Native small islets are known to have a higher insulin secretion ability in vitro and to provide better transplantation outcomes when compared w...

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Detalles Bibliográficos
Autores principales: Ichihara, Yumie, Utoh, Rie, Yamada, Masumi, Shimizu, Tatsuya, Uchigata, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946309/
https://www.ncbi.nlm.nih.gov/pubmed/27441299
http://dx.doi.org/10.1016/j.heliyon.2016.e00129