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Size effect of engineered islets prepared using microfabricated wells on islet cell function and arrangement
Pancreatic islets are heterogeneous clusters mainly composed of α and β cells, and these clusters range in diameter from 50 to several hundred micrometers. Native small islets are known to have a higher insulin secretion ability in vitro and to provide better transplantation outcomes when compared w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946309/ https://www.ncbi.nlm.nih.gov/pubmed/27441299 http://dx.doi.org/10.1016/j.heliyon.2016.e00129 |