Bystander killing effect of DS‐8201a, a novel anti‐human epidermal growth factor receptor 2 antibody–drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity

Antibody–drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window. DS‐8201a is a human epidermal growth factor receptor 2 (HER2)‐targeting antibody–drug conjugate prepared using a novel linker‐payload...

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Detalles Bibliográficos
Autores principales: Ogitani, Yusuke, Hagihara, Katsunobu, Oitate, Masataka, Naito, Hiroyuki, Agatsuma, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946713/
https://www.ncbi.nlm.nih.gov/pubmed/27166974
http://dx.doi.org/10.1111/cas.12966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946713/
https://www.ncbi.nlm.nih.gov/pubmed/27166974
http://dx.doi.org/10.1111/cas.12966

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