Identification of cooperative genes for E2A‐PBX1 to develop acute lymphoblastic leukemia

E2A‐PBX1 is a chimeric gene product detected in t(1;19)‐bearing acute lymphoblastic leukemia (ALL) with B‐cell lineage. To investigate the leukemogenic process, we generated conditional knock‐in (cKI) mice for E2A‐PBX1, in which E2A‐PBX1 is inducibly expressed under the control of the endogenous E2A...

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Detalles Bibliográficos
Autores principales: Sera, Yasuyuki, Yamasaki, Norimasa, Oda, Hideaki, Nagamachi, Akiko, Wolff, Linda, Inukai, Takeshi, Inaba, Toshiya, Honda, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946715/
https://www.ncbi.nlm.nih.gov/pubmed/27088431
http://dx.doi.org/10.1111/cas.12945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946715/
https://www.ncbi.nlm.nih.gov/pubmed/27088431
http://dx.doi.org/10.1111/cas.12945

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