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Prognostic and predictive value of extended RAS mutation and mismatch repair status in stage III colorectal cancer

The prognostic and predictive value of KRAS gene mutations in stage III colorectal cancer is controversial because many recent clinical trials have not involved a surgery‐alone arm. Additionally, data on the significance of extended RAS (KRAS/NRAS) mutations in stage III cancer are not available. He...

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Detalles Bibliográficos
Autores principales: Sasaki, Yusuke, Akasu, Takayuki, Saito, Norio, Kojima, Hiroshi, Matsuda, Keiji, Nakamori, Shoji, Komori, Koji, Amagai, Kenji, Yamaguchi, Tatsuro, Ohue, Masayuki, Nagashima, Kengo, Yamada, Yasuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946717/
https://www.ncbi.nlm.nih.gov/pubmed/27089049
http://dx.doi.org/10.1111/cas.12950