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Linkage of E2F1 transcriptional network and cell proliferation with respiratory chain activity in breast cancer cells

Mitochondria are multifunctional organelles; they have been implicated in various aspects of tumorigenesis. In this study, we investigated a novel role of the basal electron transport chain (ETC) activity in cell proliferation by inhibiting mitochondrial replication and transcription (mtR/T) using p...

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Detalles Bibliográficos
Autores principales: Mori, Kazunori, Uchida, Tetsu, Fukumura, Motonori, Tamiya, Shigetoshi, Higurashi, Masato, Sakai, Hirosato, Ishikawa, Fumihiro, Shibanuma, Motoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946721/
https://www.ncbi.nlm.nih.gov/pubmed/27094710
http://dx.doi.org/10.1111/cas.12953