CD44 variant‐dependent redox status regulation in liver fluke‐associated cholangiocarcinoma: A target for cholangiocarcinoma treatment

Expression of CD44, especially the variant isoforms (CD44v) of this major cancer stem cell marker, contributes to reactive oxygen species (ROS) defense through stabilizing xCT (a cystine–glutamate transporter) and promoting glutathione synthesis. This enhances cancer development and increases chemot...

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Detalles Bibliográficos
Autores principales: Thanee, Malinee, Loilome, Watcharin, Techasen, Anchalee, Sugihara, Eiji, Okazaki, Shogo, Abe, Shinya, Ueda, Shiho, Masuko, Takashi, Namwat, Nisana, Khuntikeo, Narong, Titapun, Attapol, Pairojkul, Chawalit, Saya, Hideyuki, Yongvanit, Puangrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946726/
https://www.ncbi.nlm.nih.gov/pubmed/27176078
http://dx.doi.org/10.1111/cas.12967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946726/
https://www.ncbi.nlm.nih.gov/pubmed/27176078
http://dx.doi.org/10.1111/cas.12967

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