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Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats

Colorectal cancer (CRC) is one of the most prevalent cancers and has a high mortality rate. Insensitivity and the limited therapeutic efficacy of its standard chemotherapeutic drug, 5-fluorouracil (5-FU), represents an important challenge in CRC treatment. The robust antitumor properties of thymoqui...

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Detalles Bibliográficos
Autores principales: Kensara, Osama Adnan, El-Shemi, Adel Galal, Mohamed, Amr Mohamed, Refaat, Bassem, Idris, Shakir, Ahmad, Jawwad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946859/
https://www.ncbi.nlm.nih.gov/pubmed/27468227
http://dx.doi.org/10.2147/DDDT.S109721