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Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats
Colorectal cancer (CRC) is one of the most prevalent cancers and has a high mortality rate. Insensitivity and the limited therapeutic efficacy of its standard chemotherapeutic drug, 5-fluorouracil (5-FU), represents an important challenge in CRC treatment. The robust antitumor properties of thymoqui...
Autores principales: | Kensara, Osama Adnan, El-Shemi, Adel Galal, Mohamed, Amr Mohamed, Refaat, Bassem, Idris, Shakir, Ahmad, Jawwad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946859/ https://www.ncbi.nlm.nih.gov/pubmed/27468227 http://dx.doi.org/10.2147/DDDT.S109721 |
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