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Crystal structure of an HIV assembly and maturation switch

Virus assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. HIV-1 contains an assembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) regi...

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Detalles Bibliográficos
Autores principales: Wagner, Jonathan M, Zadrozny, Kaneil K, Chrustowicz, Jakub, Purdy, Michael D, Yeager, Mark, Ganser-Pornillos, Barbie K, Pornillos, Owen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946879/
https://www.ncbi.nlm.nih.gov/pubmed/27416583
http://dx.doi.org/10.7554/eLife.17063