Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation

Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic variation. VSG switching occurs by frequent homologous recombination, which is thought to require locus-specific initiation. Here, we show that a RecQ helicase, RECQ2, acts to...

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Detalles Bibliográficos
Autores principales: Devlin, Rebecca, Marques, Catarina A, Paape, Daniel, Prorocic, Marko, Zurita-Leal, Andrea C, Campbell, Samantha J, Lapsley, Craig, Dickens, Nicholas, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946898/
https://www.ncbi.nlm.nih.gov/pubmed/27228154
http://dx.doi.org/10.7554/eLife.12765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946898/
https://www.ncbi.nlm.nih.gov/pubmed/27228154
http://dx.doi.org/10.7554/eLife.12765

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