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Trastuzumab-targeted gene delivery to Her2-overexpressing breast cancer cells

We describe a novel gene delivery system that specifically targets human epidermal growth factor receptor 2 (Her2)-overexpressing breast cancer cells. The targeting complexes consist of a PEGylated polylysine core that is bound to DNA molecules coding for either green fluorescent protein or shrimp l...

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Detalles Bibliográficos
Autores principales: Mann, K, Kullberg, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946976/
https://www.ncbi.nlm.nih.gov/pubmed/27199219
http://dx.doi.org/10.1038/cgt.2016.21