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An abundant class of non-coding DNA can prevent stochastic gene silencing in the C. elegans germline
Cells benefit from silencing foreign genetic elements but must simultaneously avoid inactivating endogenous genes. Although chromatin modifications and RNAs contribute to maintenance of silenced states, the establishment of silenced regions will inevitably reflect underlying DNA sequence and/or stru...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947018/ https://www.ncbi.nlm.nih.gov/pubmed/27374334 http://dx.doi.org/10.1016/j.cell.2016.05.072 |