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A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells

Thousands of long noncoding RNA (lncRNA) genes are encoded in the human genome, and hundreds of them are evolutionarily conserved, but their functions and modes of action remain largely obscure. Particularly enigmatic lncRNAs are those that are exported to the cytoplasm, including NORAD—an abundant...

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Detalles Bibliográficos
Autores principales: Tichon, Ailone, Gil, Noa, Lubelsky, Yoav, Havkin Solomon, Tal, Lemze, Doron, Itzkovitz, Shalev, Stern-Ginossar, Noam, Ulitsky, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947167/
https://www.ncbi.nlm.nih.gov/pubmed/27406171
http://dx.doi.org/10.1038/ncomms12209