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Structure of the initiation-competent RNA polymerase I and its implication for transcription

Eukaryotic RNA polymerase I (Pol I) is specialized in rRNA gene transcription synthesizing up to 60% of cellular RNA. High level rRNA production relies on efficient binding of initiation factors to the rRNA gene promoter and recruitment of Pol I complexes containing initiation factor Rrn3. Here, we...

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Detalles Bibliográficos
Autores principales: Pilsl, Michael, Crucifix, Corinne, Papai, Gabor, Krupp, Ferdinand, Steinbauer, Robert, Griesenbeck, Joachim, Milkereit, Philipp, Tschochner, Herbert, Schultz, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947174/
https://www.ncbi.nlm.nih.gov/pubmed/27418187
http://dx.doi.org/10.1038/ncomms12126