Cargando…

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

Neurons display a highly polarized microtubule network that mediates trafficking throughout the extensive cytoplasm and is crucial for neuronal differentiation and function. In newborn migrating neurons, the microtubule network is organized by the centrosome. During neuron maturation, however, the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez-Huertas, Carlos, Freixo, Francisco, Viais, Ricardo, Lacasa, Cristina, Soriano, Eduardo, Lüders, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947180/
https://www.ncbi.nlm.nih.gov/pubmed/27405868
http://dx.doi.org/10.1038/ncomms12187