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Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
Neurons display a highly polarized microtubule network that mediates trafficking throughout the extensive cytoplasm and is crucial for neuronal differentiation and function. In newborn migrating neurons, the microtubule network is organized by the centrosome. During neuron maturation, however, the c...
Autores principales: | Sánchez-Huertas, Carlos, Freixo, Francisco, Viais, Ricardo, Lacasa, Cristina, Soriano, Eduardo, Lüders, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947180/ https://www.ncbi.nlm.nih.gov/pubmed/27405868 http://dx.doi.org/10.1038/ncomms12187 |
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