The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions

Vascular homoeostasis, development and disease critically depend on the regulation of endothelial cell–cell junctions. Here we uncover a new role for the F-BAR protein pacsin2 in the control of VE-cadherin-based endothelial adhesion. Pacsin2 concentrates at focal adherens junctions (FAJs) that are e...

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Detalles Bibliográficos
Autores principales: Dorland, Yvonne L., Malinova, Tsveta S., van Stalborch, Anne-Marieke D., Grieve, Adam G., van Geemen, Daphne, Jansen, Nicolette S., de Kreuk, Bart-Jan, Nawaz, Kalim, Kole, Jeroen, Geerts, Dirk, Musters, René J. P., de Rooij, Johan, Hordijk, Peter L., Huveneers, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947187/
https://www.ncbi.nlm.nih.gov/pubmed/27417273
http://dx.doi.org/10.1038/ncomms12210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947187/
https://www.ncbi.nlm.nih.gov/pubmed/27417273
http://dx.doi.org/10.1038/ncomms12210

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