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Evaluation of intraarterial and intravenous cisplatin chemotherapy in the treatment of metastatic osteosarcoma using an orthotopic xenograft mouse model

BACKGROUND: Osteosarcoma is the most common primary malignancy of bone. Its treatment relies on the administration of neoadjuvant and adjuvant chemotherapy combined with surgery. Alternative to common intravenous (i.v.) administration of chemotherapeutic drugs, clinical studies also evaluated the be...

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Detalles Bibliográficos
Autores principales: Robl, Bernhard, Botter, Sander Martijn, Pellegrini, Giovanni, Neklyudova, Olga, Fuchs, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947253/
https://www.ncbi.nlm.nih.gov/pubmed/27421768
http://dx.doi.org/10.1186/s13046-016-0392-1