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Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

BACKGROUND: Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (BAL) fluid biomarkers have previously been shown...

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Detalles Bibliográficos
Autores principales: Hellyer, Thomas P., Anderson, Niall H., Parker, Jennie, Dark, Paul, Van Den Broeck, Tina, Singh, Suveer, McMullan, Ronan, Agus, Ashley M., Emerson, Lydia M., Blackwood, Bronagh, Gossain, Savita, Walsh, Tim S., Perkins, Gavin D., Conway Morris, Andrew, McAuley, Daniel F., Simpson, A. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947254/
https://www.ncbi.nlm.nih.gov/pubmed/27422026
http://dx.doi.org/10.1186/s13063-016-1442-x