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Effectiveness of AMD3100 in treatment of leukemia and solid tumors: from original discovery to use in current clinical practice
AMD3100, also known as plerixafor, was originally developed as an anti-human immunodeficiency virus (HIV) drug, and later characterized as a C-X-C chemokine receptor type 4 (CXCR4) antagonist. Previous reviews have focused on the application of AMD3100 in the treatment of HIV, but a comprehensive ev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947283/ https://www.ncbi.nlm.nih.gov/pubmed/27429863 http://dx.doi.org/10.1186/s40164-016-0050-5 |