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Inhomogeneity of immune cell composition in the synovial sublining: linear mixed modelling indicates differences in distribution and spatial decline of CD68+ macrophages in osteoarthritis and rheumatoid arthritis

BACKGROUND: Inhomogeneity of immune cell distribution in the synovial sublining layer was analyzed in order to improve our mechanistic understanding of synovial inflammation and explore potential refinements for histological biomarkers in rheumatoid arthritis (RA) and osteoarthritis (OA). METHODS: S...

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Detalles Bibliográficos
Autores principales: Mucke, Johanna, Hoyer, Annika, Brinks, Ralph, Bleck, Ellen, Pauly, Thomas, Schneider, Matthias, Vordenbäumen, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947315/
https://www.ncbi.nlm.nih.gov/pubmed/27424032
http://dx.doi.org/10.1186/s13075-016-1057-3