Safety and pharmacodynamic dose response of short-term prednisone in healthy adult subjects: a dose ranging, randomized, placebo-controlled, crossover study

BACKGROUND: Glucocorticoids (GCs), such as prednisone, are the standard of care for several inflammatory and immunologically mediated diseases, but their chronic systemic administration is severely limited by serious adverse effects that are both dose and time dependent. Short-term treatment (7–14 d...

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Detalles Bibliográficos
Autores principales: Fleishaker, Dona L., Mukherjee, Arnab, Whaley, Fredrick S., Daniel, Shanthini, Zeiher, Bernhardt G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947329/
https://www.ncbi.nlm.nih.gov/pubmed/27424036
http://dx.doi.org/10.1186/s12891-016-1135-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947329/
https://www.ncbi.nlm.nih.gov/pubmed/27424036
http://dx.doi.org/10.1186/s12891-016-1135-3

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