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Biases affecting injected doses of an experimental drug during clinical trials

BACKGROUND: During clinical trials, researchers rarely question nominal doses specified on labels of investigational products, overlooking the potential for inaccuracies that may result when calculating pharmacokinetic and pharmacodynamic parameters. This study evaluated the disparity between nomina...

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Detalles Bibliográficos
Autores principales: Perrottet, Nancy, Brunner-Ferber, Françoise, Grouzmann, Eric, Spertini, François, Biollaz, Jérôme, Buclin, Thierry, Widmer, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947517/
https://www.ncbi.nlm.nih.gov/pubmed/27423899
http://dx.doi.org/10.1186/s13063-016-1463-5