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Biases affecting injected doses of an experimental drug during clinical trials
BACKGROUND: During clinical trials, researchers rarely question nominal doses specified on labels of investigational products, overlooking the potential for inaccuracies that may result when calculating pharmacokinetic and pharmacodynamic parameters. This study evaluated the disparity between nomina...
Autores principales: | Perrottet, Nancy, Brunner-Ferber, Françoise, Grouzmann, Eric, Spertini, François, Biollaz, Jérôme, Buclin, Thierry, Widmer, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947517/ https://www.ncbi.nlm.nih.gov/pubmed/27423899 http://dx.doi.org/10.1186/s13063-016-1463-5 |
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