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Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

Eukaryotic genomes are partitioned into chromosomes, which during mitosis form compact and spatially well-separated mechanical bodies1–3.This enables chromosomes to move independently of each other for segregation of precisely one copy of the genome to each of the nascent daughter cells. Despite ins...

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Detalles Bibliográficos
Autores principales: Cuylen, Sara, Blaukopf, Claudia, Politi, Antonio Z., Müller-Reichert, Thomas, Neumann, Beate, Poser, Ina, Ellenberg, Jan, Hyman, Anthony A., Gerlich, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947524/
https://www.ncbi.nlm.nih.gov/pubmed/27362226
http://dx.doi.org/10.1038/nature18610