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Rosuvastatin intensifies the beneficial effects of rho-kinase inhibitor in reversal of monocrotaline-induced pulmonary hypertension

INTRODUCTION: It remains controversial whether statins have a beneficial effect on pulmonary arterial hypertension (PAH). This study is intended to evaluate whether statin, co-administered with Rho-kinase inhibitor, could enhance its efficacy. Although Rho-kinase inhibitors, including fasudil, have...

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Detalles Bibliográficos
Autores principales: Jasińska-Stroschein, Magdalena, Owczarek, Jacek, Sołtysiak, Urszula, Orszulak-Michalak, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947607/
https://www.ncbi.nlm.nih.gov/pubmed/27478473
http://dx.doi.org/10.5114/aoms.2015.49740