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Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION)

INTRODUCTION: Gastrointestinal dysmotility and constipation are common problems in intensive care patients. The majority of critical care patients are sedated with opioids to facilitate tolerance of endotracheal tubes and mechanical ventilation, which inhibit gastrointestinal motility and lead to ad...

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Detalles Bibliográficos
Autores principales: Patel, Parind B, Brett, Stephen J, O'Callaghan, David, Anjum, Aisha, Cross, Mary, Warwick, Jane, Gordon, Anthony C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947806/
https://www.ncbi.nlm.nih.gov/pubmed/27412108
http://dx.doi.org/10.1136/bmjopen-2016-011750