The limitations of qPCR telomere length measurement in diagnosing dyskeratosis congenita

BACKGROUND: Telomere length <1st percentile‐for‐age in leukocyte subsets by flow cytometry with fluorescence in situ hybridization (flow FISH) is highly sensitive and specific in diagnosing patients with dyskeratosis congenita (DC), a telomere biology disorder. METHODS: We evaluated the clinical...

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Detalles Bibliográficos
Autores principales: Gadalla, Shahinaz M., Khincha, Payal P., Katki, Hormuzd A., Giri, Neelam, Wong, Jason Y. Y., Spellman, Stephen, Yanovski, Jack A., Han, Joan C., De Vivo, Immaculata, Alter, Blanche P., Savage, Sharon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947866/
https://www.ncbi.nlm.nih.gov/pubmed/27468421
http://dx.doi.org/10.1002/mgg3.220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947866/
https://www.ncbi.nlm.nih.gov/pubmed/27468421
http://dx.doi.org/10.1002/mgg3.220

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