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Dual Topology of the Melanocortin-2 Receptor Accessory Protein Is Stable

Melanocortin 2 receptor accessory protein (MRAP) facilitates trafficking of melanocortin 2 (MC2) receptors and is essential for ACTH binding and signaling. MRAP is a single transmembrane domain protein that forms antiparallel homodimers. These studies ask when MRAP first acquires this dual topology,...

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Detalles Bibliográficos
Autores principales: Maben, Zachary J., Malik, Sundeep, Jiang, Liyi H., Hinkle, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947873/
https://www.ncbi.nlm.nih.gov/pubmed/27486435
http://dx.doi.org/10.3389/fendo.2016.00096