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Association of germline genetic variants in RFC, IL15 and VDR genes with minimal residual disease in pediatric B-cell precursor ALL

Minimal residual disease (MRD) enables reliable assessment of risk in acute lymphoblastic leukemia (ALL). However, little is known on association between MRD status and germline genetic variation. We examined 159 Caucasian (Slavic) patients with pediatric ALL, treated according to ALL-IC-BFM 2002/20...

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Detalles Bibliográficos
Autores principales: Dawidowska, Małgorzata, Kosmalska, Maria, Sędek, Łukasz, Szczepankiewicz, Aleksandra, Twardoch, Magdalena, Sonsala, Alicja, Szarzyńska-Zawadzka, Bronisława, Derwich, Katarzyna, Lejman, Monika, Pawelec, Katarzyna, Obitko-Płudowska, Agnieszka, Pawińska-Wąsikowska, Katarzyna, Kwiecińska, Kinga, Kołtan, Andrzej, Dyla, Agnieszka, Grzeszczak, Władysław, Kowalczyk, Jerzy R., Szczepański, Tomasz, Ziętkiewicz, Ewa, Witt, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947903/
https://www.ncbi.nlm.nih.gov/pubmed/27427275
http://dx.doi.org/10.1038/srep29427