Lupin Peptides Modulate the Protein-Protein Interaction of PCSK9 with the Low Density Lipoprotein Receptor in HepG2 Cells

Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been recently identified as a new useful target for hypercholesterolemia treatment. This work demonstrates that natural peptides, deriving from the hydrolysis of lupin protein and absorbable at intestinal level, are able to inhibit the protei...

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Detalles Bibliográficos
Autores principales: Lammi, Carmen, Zanoni, Chiara, Aiello, Gilda, Arnoldi, Anna, Grazioso, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947907/
https://www.ncbi.nlm.nih.gov/pubmed/27424515
http://dx.doi.org/10.1038/srep29931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947907/
https://www.ncbi.nlm.nih.gov/pubmed/27424515
http://dx.doi.org/10.1038/srep29931

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