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Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

Hypoxia is a hallmark of cancer that is strongly associated with invasion, metastasis, resistance to therapy and poor clinical outcome. Tumour hypoxia affects immune responses and promotes the accumulation of macrophages in the tumour microenvironment. However, the signals linking tumour hypoxia to...

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Detalles Bibliográficos
Autores principales: Huber, Roman, Meier, Barbara, Otsuka, Atsushi, Fenini, Gabriele, Satoh, Takashi, Gehrke, Samuel, Widmer, Daniel, Levesque, Mitchell P., Mangana, Joanna, Kerl, Katrin, Gebhardt, Christoffer, Fujii, Hiroko, Nakashima, Chisa, Nonomura, Yumi, Kabashima, Kenji, Dummer, Reinhard, Contassot, Emmanuel, French, Lars E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947927/
https://www.ncbi.nlm.nih.gov/pubmed/27426915
http://dx.doi.org/10.1038/srep29914