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Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages
Hypoxia is a hallmark of cancer that is strongly associated with invasion, metastasis, resistance to therapy and poor clinical outcome. Tumour hypoxia affects immune responses and promotes the accumulation of macrophages in the tumour microenvironment. However, the signals linking tumour hypoxia to...
Autores principales: | Huber, Roman, Meier, Barbara, Otsuka, Atsushi, Fenini, Gabriele, Satoh, Takashi, Gehrke, Samuel, Widmer, Daniel, Levesque, Mitchell P., Mangana, Joanna, Kerl, Katrin, Gebhardt, Christoffer, Fujii, Hiroko, Nakashima, Chisa, Nonomura, Yumi, Kabashima, Kenji, Dummer, Reinhard, Contassot, Emmanuel, French, Lars E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947927/ https://www.ncbi.nlm.nih.gov/pubmed/27426915 http://dx.doi.org/10.1038/srep29914 |
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