Tyrosine triple mutated AAV2-BDNF gene therapy in a rat model of transient IOP elevation

PURPOSE: We examined the neuroprotective effects of exogenous brain-derived neurotrophic factor (BDNF), which provides protection to retinal ganglion cells (RGCs) in rodents, in a model of transient intraocular pressure (IOP) elevation using a mutant (triple Y-F) self-complementary adeno-associated...

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Detalles Bibliográficos
Autores principales: Igarashi, Tsutomu, Miyake, Koichi, Kobayashi, Maika, Kameya, Shuhei, Fujimoto, Chiaki, Nakamoto, Kenji, Takahashi, Hisatomo, Igarashi, Toru, Miyake, Noriko, Iijima, Osamu, Hirai, Yukihiko, Shimada, Takashi, Okada, Takashi, Takahashi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947967/
https://www.ncbi.nlm.nih.gov/pubmed/27440998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947967/
https://www.ncbi.nlm.nih.gov/pubmed/27440998

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