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Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers

Non-biological synthetic oligomers can serve as ligands for antibodies. We hypothesized that a random combinatorial library of synthetic poly-N-substituted glycine oligomers, or peptoids, could represent a random “shape library” in antigen space, and that some of these peptoids would be recognized b...

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Detalles Bibliográficos
Autores principales: Gearhart, Tricia L., Montelaro, Ronald C., Schurdak, Mark E., Pilcher, Chris D., Rinaldo, Charles R., Kodadek, Thomas, Park, Yongseok, Islam, Kazi, Yurko, Raymond, Marques, Ernesto T.A., Burke, Donald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947968/
https://www.ncbi.nlm.nih.gov/pubmed/27182050
http://dx.doi.org/10.1016/j.jim.2016.05.001