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Phenotypic Assessment and the Discovery of Topiramate

[Image: see text] The role of phenotypic assessment in drug discovery is discussed, along with the discovery and development of TOPAMAX (topiramate), a billion-dollar molecule for the treatment of epilepsy and migraine.

Detalles Bibliográficos
Autor principal: Maryanoff, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948003/
https://www.ncbi.nlm.nih.gov/pubmed/27437073
http://dx.doi.org/10.1021/acsmedchemlett.6b00176