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Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy

The genetic modification and characterization of T-cells with chimeric antigen receptors (CARs) allow functionally distinct T-cell subsets to recognize specific tumor cells. The incorporation of costimulatory molecules or cytokines can enable engineered T-cells to eliminate tumor cells. CARs are gen...

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Detalles Bibliográficos
Autores principales: Dai, Hanren, Wang, Yao, Lu, Xuechun, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948566/
https://www.ncbi.nlm.nih.gov/pubmed/26819347
http://dx.doi.org/10.1093/jnci/djv439