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Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
Despite research efforts, cell uptake processes determining siRNA silencing efficiency remain unclear. Here, we examine the relationship between in vitro cell culture models, cellular trafficking and siRNA silencing efficiency to provide a mechanistic insight on siRNA delivery system design. Model s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948577/ https://www.ncbi.nlm.nih.gov/pubmed/27349867 http://dx.doi.org/10.1016/j.bbrc.2016.06.054 |