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Genetic basis of Cowden syndrome and its implications for clinical practice and risk management

Cowden syndrome (CS) is an often difficult to recognize hereditary cancer predisposition syndrome caused by mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN). In addition to conferring increased cancer risks, CS also predisposes individuals to developing hamartomatous growt...

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Detalles Bibliográficos
Autores principales: Gammon, Amanda, Jasperson, Kory, Champine, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948690/
https://www.ncbi.nlm.nih.gov/pubmed/27471403
http://dx.doi.org/10.2147/TACG.S41947