Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial–mesenchymal transition, invasion, and metastasis in pancreatic cancer cells

Interleukin (IL)-32 is a newly discovered cytokine that has multifaceted roles in inflammatory bowel disease, cancer, and autoimmune diseases and participates in cell apoptosis, cancer cell growth inhibition, accentuation of inflammation, and angiogenesis. Here, we investigated the potential effects...

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Detalles Bibliográficos
Autores principales: Chen, Jingfeng, Wang, Silu, Su, Jiadong, Chu, Guanyu, You, Heyi, Chen, Zongjing, Sun, Hongwei, Chen, Bicheng, Zhou, Mengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948719/
https://www.ncbi.nlm.nih.gov/pubmed/27471397
http://dx.doi.org/10.2147/OTT.S103581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948719/
https://www.ncbi.nlm.nih.gov/pubmed/27471397
http://dx.doi.org/10.2147/OTT.S103581

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