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Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial–mesenchymal transition, invasion, and metastasis in pancreatic cancer cells
Interleukin (IL)-32 is a newly discovered cytokine that has multifaceted roles in inflammatory bowel disease, cancer, and autoimmune diseases and participates in cell apoptosis, cancer cell growth inhibition, accentuation of inflammation, and angiogenesis. Here, we investigated the potential effects...
Autores principales: | Chen, Jingfeng, Wang, Silu, Su, Jiadong, Chu, Guanyu, You, Heyi, Chen, Zongjing, Sun, Hongwei, Chen, Bicheng, Zhou, Mengtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948719/ https://www.ncbi.nlm.nih.gov/pubmed/27471397 http://dx.doi.org/10.2147/OTT.S103581 |
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