Population pharmacokinetic modeling of glibenclamide in poorly controlled South African type 2 diabetic subjects

AIM: The aim of this study was to describe the pharmacokinetics (PK) of glibenclamide in poorly controlled South African type 2 diabetic subjects using noncompartmental and model-based methods. METHODS: A total of 24 subjects with type 2 diabetes were administered increasing doses (0 mg/d, 2.5 mg/d,...

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Detalles Bibliográficos
Autores principales: Rambiritch, Virendra, Naidoo, Poobalan, Maharaj, Breminand, Pillai, Goonaseelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948726/
https://www.ncbi.nlm.nih.gov/pubmed/27471411
http://dx.doi.org/10.2147/CPAA.S102676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948726/
https://www.ncbi.nlm.nih.gov/pubmed/27471411
http://dx.doi.org/10.2147/CPAA.S102676

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