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Mycobacterium tuberculosis Induces Expansion of Foxp3 Positive CD4 T-cells with a Regulatory Profile in Tuberculin Non-sensitized Healthy Subjects: Implications for Effective Immunization against TB

OBJECTIVE: Infection by MTB or exposure to MTB constituents is associated with intense microbial stimulation of the immune system, through both antigenic and TLR components, and induction of a milieu that is rich in pro-inflammatory/anti-inflammatory cytokines. Here, we addressed the basis of induce...

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Detalles Bibliográficos
Autores principales: Hirsch, Christina S, Rojas, Roxana, Wu, Mianda, Toossi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948752/
https://www.ncbi.nlm.nih.gov/pubmed/27441095
http://dx.doi.org/10.4172/2155-9899.1000428