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Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster

Lysozyme amyloidosis is a hereditary disease in which mutations in the gene coding for lysozyme leads to misfolding and consequently accumulation of amyloid material. To improve understanding of the processes involved we expressed human wild type (WT) lysozyme and the disease-associated variant F57I...

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Detalles Bibliográficos
Autores principales: Helmfors, Linda, Bergkvist, Liza, Brorsson, Ann-Christin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948765/
https://www.ncbi.nlm.nih.gov/pubmed/27428539
http://dx.doi.org/10.1371/journal.pone.0159294