The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS

The eukaryotic protein Isd11 is a chaperone that binds and stabilizes the central component of the essential metabolic pathway responsible for formation of iron-sulfur clusters in mitochondria, the desulfurase Nfs1. Little is known about the exact role of Isd11. Here, we show that human Isd11 (ISD11...

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Detalles Bibliográficos
Autores principales: Yan, Robert, Friemel, Martin, Aloisi, Claudia, Huynen, Martijn, Taylor, Ian A., Leimkühler, Silke, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948766/
https://www.ncbi.nlm.nih.gov/pubmed/27427956
http://dx.doi.org/10.1371/journal.pone.0157895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948766/
https://www.ncbi.nlm.nih.gov/pubmed/27427956
http://dx.doi.org/10.1371/journal.pone.0157895

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