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The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS
The eukaryotic protein Isd11 is a chaperone that binds and stabilizes the central component of the essential metabolic pathway responsible for formation of iron-sulfur clusters in mitochondria, the desulfurase Nfs1. Little is known about the exact role of Isd11. Here, we show that human Isd11 (ISD11...
Autores principales: | Yan, Robert, Friemel, Martin, Aloisi, Claudia, Huynen, Martijn, Taylor, Ian A., Leimkühler, Silke, Pastore, Annalisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948766/ https://www.ncbi.nlm.nih.gov/pubmed/27427956 http://dx.doi.org/10.1371/journal.pone.0157895 |
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