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Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury

Traumatic brain injury (TBI) is an established risk factor for the development of Alzheimer’s disease (AD). Here the effects of severe penetrating TBI on APP and tau cleavage processing were investigated in a rodent model of penetrating ballistic-like brain injury (PBBI). PBBI was induced by stereot...

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Detalles Bibliográficos
Autores principales: Cartagena, Casandra M., Mountney, Andrea, Hwang, Hye, Swiercz, Adam, Rammelkamp, Zoe, Boutte, Angela M., Shear, Deborah A., Tortella, Frank C., Schmid, Kara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948774/
https://www.ncbi.nlm.nih.gov/pubmed/27428544
http://dx.doi.org/10.1371/journal.pone.0158576