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Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae

DNA methylation is an important epigenetic mechanism for phenotypic diversification in all forms of life. We previously described remarkable cell-to-cell heterogeneity in epigenetic pattern within a clonal population of Streptococcus pneumoniae, a leading human pathogen. We here report that the epig...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Jing-Wen, Feng, Zhixing, Wang, Juanjuan, An, Haoran, Liu, Yanni, Wang, Yang, Wang, Kailing, Zhang, Xuegong, Miao, Zhun, Liang, Wenbo, Sebra, Robert, Wang, Guilin, Wang, Wen-Ching, Zhang, Jing-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948785/
https://www.ncbi.nlm.nih.gov/pubmed/27427949
http://dx.doi.org/10.1371/journal.ppat.1005762